New Treatment Strategies and Considerations in OAB to Improve Patient Outcomes (Archived Online CME/CE Monograph)

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Activity Description and Purpose

Overactive bladder (OAB) syndrome has a negative effect on a patient’s independence, emotional wellbeing, work productivity, and overall quality of life. Although treatments are available in various forms, increasing evidence suggests that some medications that are commonly used to treat OAB pose a risk of cognitive decline, especially in older populations and in patients with a history of cognitive impairment. This educational activity is based on the proceedings of several symposia on OAB that reviewed updates in the treatment of OAB, including clinical data on new and emerging treatments, and which highlighted some of the evidence on the increased risk of dementia associated with antimuscarinic use.

Target Audience

This educational activity is intended for urologists, urogynecologists, physician assistants, nurse practitioners, nurses, and other clinicians involved in the care of patients with overactive bladder.

Learning Objectives

After completing this activity, participants will be better able to:

  • Review the data on central nervous system effects of antimuscarinic overactive bladder medications and β3-adrenoceptor agonists
  • Review clinical trial data on new and emerging treatments for overactive bladder
  • Develop appropriate treatment strategies for patients with overactive bladder
Course summary
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Roger Dmochowski, MD, MMHC, FACS (Chair)
Associate Surgeon in Chief
Professor of Urology
Professor of Surgery
Professor of Obstetrics and Gynecology
Vice Chair, Section of Surgical Sciences
Vanderbilt University Medical Center
Nashville, Tennessee
Benjamin M. Brucker, MD
Associate Professor
Departments of Urology and Obstetrics and Gynecology
Director, Female Pelvic Medicine and Reconstructive Surgery Program and Neurourology
New York University Langone Health
New York, New York
Ekene Enemchukwu, MD, MPH, FACS, FPMRS
Assistant Professor of Urology
Assistant Professor of Obstetrics and Gynecology (Urogynecology), by Courtesy
Medical Director, Stanford Multidisciplinary Pelvic Health Center
Female Pelvic Medicine and Reconstructive Surgery
Male Voiding Dysfunction and Neurourology
Stanford University School of Medicine
Palo Alto, California
Stephanie Kielb, MD
Professor of Urology, Medical Education, and OB/GYN
Division Chief, Reconstruction, Neurology, and Pelvic Medicine
Residency Program Director
Department of Urology
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Peter Sand, MD (Chair)
Clinical Professor of Obstetrics and Gynecology
University of Chicago, Pritzker School of Medicine
Director of Urogynecology Research
Division of Urogynecology
Department of Obstetrics and Gynecology
NorthShore University HealthSystem
Chicago, Illinois
Alan J. Wein, MD, PhD (Hon), FACS
Professor With Tenure and Emeritus Chief of Urology
Associate Director, Residency Program in Urology
Penn Medicine
Perelman School of Medicine
University of Pennsylvania Health System
Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania

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MedEdicus adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been identified and mitigated by MedEdicus prior to the commencement of the activity.



Benjamin M. Brucker, MD, is a consultant for Antares Pharma and Click Therapeutics, Inc; is on the speakers bureau for Allergan and Urovant Sciences, Inc; and has individual stocks or stock options in Watkins-Conti Products, Inc.

Roger Dmochowski, MD, is a consultant for BlueWind Medical, Caldera Medical, and Viveve.

Ekene Enemchukwu, MD, MPH, is a consultant for Avation Medical, Boston Scientific Corporation, and Urovant Sciences, Inc.

Stephanie Kielb, MD, has no relevant commercial relationships to disclose.

Peter K. Sand, MD, is a consultant for Allergan, Astellas Pharma US, Inc, EBT Medical, and Valencia Technologies Corporation; is on the speakers bureau for Allergan, Astellas Pharma US, Inc, and Urovant Sciences, Inc; and is a contracted researcher for BlueWind Medical, Medtronic, and Valencia Technologies Corporation.

Alan J. Wein, MD, PhD (Hon), is a consultant for Antares Pharma, Urovant Sciences, Inc, and Viveve.

Peer Reviewer

This activity was peer reviewed. The peer reviewer has no relevant commercial relationships to disclose.

Planners and Managers

MedEdicus planners and managers have no relevant commercial relationships to disclose.

For Physicians

ACCME Accreditation Statement

 MedEdicus LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA PRA Credit Designation Statement

MedEdicus LLC designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For Nurses

Interprofessional Joint Accreditation Statement

image In support of improving patient care, this activity has been planned and implemented by MedEdicus LLC and Amedco LLC. Amedco LLC is jointly accredited by the ACCME, the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Nurses (ANCC) Credit Designation

Amedco LLC designates this activity for a maximum of 1.5 ANCC contact hours.

Disclosure of Commercial Support

This continuing medical education activity is supported through an educational grant from Urovant Sciences, Inc.

Off-Label Discussion

This educational activity may include discussion of unlabeled and/or investigational uses of drugs and devices. Please refer to the official prescribing information for each drug or device discussed in this activity for approved dosing, indications, and warnings.

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The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of MedEdicus LLC, Amedco LLC, or Urovant Sciences, Inc.

This CME/CE activity is copyrighted to MedEdicus LLC ©2022. All rights reserved. 253.4

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This educational activity has expired. You will not be able to claim credit for this activity.