Individualizing Treatment of Neovascular AMD in the Digital Age: Focus on Retinal Fluid Prognosticators (Archive CME Monograph)
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Activity Description and Purpose
Age-related macular degeneration (AMD) is a leading cause of vision loss in Canada, preferentially affecting White patients aged ≥ 75 years. The prevalence of vision-threatening advanced AMD is also steadily increasing as the population ages. The standard of care for neovascular AMD (nAMD) is anti–vascular endothelial growth factor injections, but a growing body of real-world studies indicates that patients do not achieve comparable visual acuity outcomes to those in landmark clinical trials. In particular, patients in Canada are older and have poorer visual acuity at diagnosis, leading to poor long-term visual outcomes, compared with those in other developed countries. To address these unmet needs, accumulating evidence supports regular disease screening and monitoring using optical coherence tomography and individualized dosing. In rural areas, and considering the ongoing COVID-19 pandemic, frequent monitoring and image interpretation present challenges that may be overcome using artificial intelligence and newer technologies. In this educational activity, derived from a roundtable discussion, experts interpret the latest data and provide actionable insights to meet the needs of Canadians with nAMD or those at risk of development of nAMD in a previously unaffected eye. The desired outcomes of this activity are for retina specialists and other ophthalmologists to better evaluate recent research on the clinical relevance of fluid on optical coherence tomography and apply the evidence to assess current and emerging treatment strategies and therapies.
Target Audience
This educational activity is intended for retina specialists and other ophthalmologists caring for patients with nAMD.
Learning Objectives
After completing this activity, participants will be better able to:
- Develop strategies for earlier diagnosis of conversion from dry to wet AMD
- Discuss the clinical relevance of retinal fluid subtypes as they pertain to visual acuity outcomes
- Compare strategies for monitoring and measuring retinal fluid in-office and remotely using artificial intelligence
- Adapt long-term treatment plans for patients with nAMD according to optical coherence tomography findings
Faculty
Michael Singer, MD (Chair) Clinical Professor of Ophthalmology University of Texas Health Science Center Director of Clinical Research Medical Center Ophthalmology Associates San Antonio, Texas | |
Usha Chakravarthy, MD, PhD Professor, Ophthalmology and Vision Sciences Royal Victoria Hospital (The Belfast Trust) and Queens University of Belfast Belfast, United Kingdom | |
Peter Kertes, MD, CM, FRCSC Professor of Ophthalmology and Vision Sciences University of Toronto Retina Specialist Sunnybrook Health Sciences Centre Toronto, Canada | |
David T. Wong, MD, FRCSC Associate Professor Department of Ophthalmology and Vision Sciences University of Toronto Ophthalmologist-in-Chief Unity Health – St Michael’s Hospital Toronto, Canada |
Disclosure Policy
MedEdicus requires that anyone who is in a position to control the content of this educational activity disclose all relevant financial relationships with any commercial interest. Financial relationship information is collected and resolved prior to the educational activity.
Faculty
Usha Chakravarthy, MD, PhD, is on the speakers bureau for Novartis Pharmaceuticals Corporation.
Peter Kertes, MD, CM, is a consultant for Bayer Inc, F. Hoffmann-La Roche Ltd, Novartis Pharmaceuticals Corporation, Novelty Nobility Inc, and Zeiss; is on the speakers bureau for Bayer Inc; is a contracted researcher for Bayer Inc, F. Hoffmann-La Roche Ltd, and Novartis Pharmaceuticals Corporation; and has ownership interest (stocks) in ArcticDX Inc.
Michael Singer, MD, is a consultant for Allergan, EyePoint Pharmaceuticals, Genentech, Inc, Novartis Pharmaceuticals Corporation, and Regeneron Pharmaceuticals, Inc; is on the speakers bureau for Allergan, EyePoint Pharmaceuticals, Genentech, Inc, Novartis Pharmaceuticals Corporation, and Regeneron Pharmaceuticals, Inc; is a contracted researcher for Aerie Pharmaceuticals, Inc, Allegro Ophthalmics, LLC, Allergan, Genentech, Inc, ICON plc, Ionis Pharmaceuticals, Inc, KalVista Pharmaceuticals, Kodiak Sciences Inc, Novartis Pharmaceuticals Corporation, Opthea, Optos, Regeneron Pharmaceuticals, Inc, Ribomic, Santen Inc, Senju Pharmaceutical Co, Ltd, and Sydnexis Inc; and has ownership interest (stocks) in Aviceda Therapeutics and Nanoscope Technologies LLC.
David T. Wong, MD, is a consultant for Bausch & Lomb Incorporated, Bayer Inc, F. Hoffmann-La Roche Ltd, and Novartis Pharmaceuticals Corporation; is a contracted researcher for F. Hoffmann-La Roche Ltd and Novartis Pharmaceuticals Corporation; and has ownership interest (stocks) in ArcticDX Inc.
Peer Reviewer
This activity was peer reviewed. The peer reviewer has no relevant commercial relationships to disclose.
Planners and Managers
MedEdicus planners and managers have no relevant commercial relationships to disclose.
Accreditation Statement
MedEdicus LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation Statement
MedEdicus LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosure of Commercial Support
This continuing medical education activity is supported through an educational grant from Bayer Inc.
Off-Label Discussion
This educational activity may include discussion of unlabeled and/or investigational uses of drugs and devices. Please refer to the official prescribing information for each drug or device discussed in this activity for approved dosing, indications, and warnings.
Provider Contact Information
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Disclaimer
The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of MedEdicus LLC or Allergan.
This continuing medical education activity is provided by MedEdicus LLC.
This continuing medical education activity is supported through an educational grant from Bayer Inc.
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