Below the Surface: Targeting the Corneal Nerve in the Treatment of Ocular Conditions (CME Symposium)

Activity Description

The corneal nerve contributes to the health and homeostasis of the ocular surface by playing a role in tear secretion, trophic support to epithelial and stromal cells of the cornea, and protective reflexes. When corneal nerve fibers are impaired or destroyed—either by disease, infection, injury, or the result of refractive surgical procedures—this dysfunction can lead to serious visual consequences, including blindness. This educational activity will review the role and function of the corneal nerve in both states of health and disease.

Target Audience

This educational activity is intended for ophthalmologists.

Learning Objectives

After completing this activity, participants will be better able to:

  • Review the role of the corneal nerve in maintaining ocular surface homeostasis
  • Review the neurosensory etiologies of ocular surface diseases
  • Review strategies for diagnosing diseases related to corneal nerve dysfunction
  • Select optimal treatment strategies for patients with diseases related to corneal nerve dysfunction
Course summary
Available credit: 
  • 1.50 AMA PRA Category 1 Credit™
  • 1.50 Participation
Course opens: 
Course expires: 


Preeya K. Gupta, MD (Chair)
Managing Director
Triangle Eye Consultants
Raleigh, North Carolina
Adjunct Associate Professor of Ophthalmology
Cornea, Cataract, & Refractive Surgery
Tulane University
New Orleans, Louisiana
Pedram Hamrah, MD
Professor and Interim Chairman
Co-Director, Cornea Service
Department of Ophthalmology
Tufts Medical Center
Tufts University School of Medicine
Boston, Massachusetts
Melissa Toyos, MD
Partner and Director of Research
Toyos Clinic
Nashville, Tennessee

Disclosure Policy

MedEdicus adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been identified and mitigated by MedEdicus prior to the commencement of the activity.


Preeya K. Gupta, MD, is a consultant for Alcon, Aldeyra Therapeutics, Allergan, Azura Ophthalmics Ltd, Expert Opinion, Hanall Biopharma, Johnson & Johnson Vision Care, Inc, Kala Pharmaceuticals, New World Medical, Inc, Novartis Pharmaceuticals Corporation, Ocular Science, Oyster Point Pharma, Inc, Sight Sciences, Sun Pharmaceutical Industries, Inc, Surface Pharmaceuticals Inc, TearClear, TearLab Corporation, TissueTech, Inc, Visionology, and Zeiss.

Pedram Hamrah, MD, is a consultant for Kala Pharmaceuticals and Santen Inc; is an advisory board member of Dompé US, Inc, Hawkeye Therapeutics, Novartis Pharmaceuticals Corporation, Noveome Biotherapeutics, Inc, and Oyster Point Pharma, Inc; and is a contracted researcher for Claris Biotherapeutics, CooperVision, Dompé US, Inc, Novartis Pharmaceuticals Corporation, Noveome Biotherapeutics, Inc, Ocular Therapeutix, Inc, OKYO Pharma, Limited, and Oyster Point Pharma, Inc.

Melissa Toyos, MD, is a consultant for Bausch & Lomb Incorporated, Mallinckrodt, and RVL Pharmaceuticals, Inc; is a contracted researcher for Allysta Pharmaceuticals, Inc, Bausch & Lomb Incorporated, GreenLight Medicines, Lumenis, and Novartis Pharmaceuticals Corporation; and is on the speakers bureau for Bausch & Lomb Incorporated, Mallinckrodt, and RVL Pharmaceuticals, Inc.

Peer Reviewer

This activity was peer reviewed. The peer reviewer has no relevant commercial relationships to disclose.

Planners, Managers, and Writers

MedEdicus planners, managers, and writers have no relevant commercial relationships to disclose.

Accreditation Statement

MedEdicus LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

MedEdicus LLC designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Commercial Support

This continuing medical education activity is supported through an educational grant from Dompé US, Inc.

Off-Label Discussion

This educational activity may include discussion of unlabeled and/or investigational uses of drugs and devices. Please refer to the official prescribing information for each drug or device discussed in this activity for approved dosing, indications, and warnings.

Provider Contact Information

For questions about this educational activity, please contact MedEdicus LLC at


The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of MedEdicus LLC or Dompé US, Inc.

©2022 MedEdicus LLC. 281.1

Available Credit

  • 1.50 AMA PRA Category 1 Credit™
  • 1.50 Participation
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